The discussion in European research evolves around a paradigm shift in nursing research from descriptive studies towards intervention research purposive to support evidence-based practice and nursing care. Since nursing consists of many complex actions, it is natural to focus on intervention and implementation research. One solution could be to use Medical Recearch Council's framework for development and evaluation of complex interventions, which provides guidelines and methodologies that can be advantageous for further development of clinical nursing. The aim of this article is to describe how the MRC-framework can be used as a research design to develop and evaluate complex interventions in clinical nursing. The article will be based on examples of considerations and choices from a Danish intervention study designed to evaluate a case management program with home visits to the elderly who live alone, after a total hip replacement through an accelerated orthopedic surgical process The HOOPLA-project.

Keywords: Complex, evidence-based practice, intervention, MRC, Nursing, orthopaedic