More than 700,000 Danes have to live with chronic pain. This paper presents and discusses Saunders’ idea of Total Pain and various perspectives of pain and suffering in order to create a pattern of the implications the various ideas can have on the nurse’s attitude and on the alleviation of the patient’s pain and suffering – on Total Pain. This paper gives examples of how Total Pain can be identified and described as a meaningful sign in the interpersonal relations between nurse and patient, and in the nursing diagnosis.